One Cell. SNVs and CNVs.

Because the change in our blueprint is where cancer begins.

The only single-cell targeted DNA solution that provides both copy number variants (CNVs) and single nucleotide variants (SNVs) from the same cell. Characterize genomic heterogeneity using a single platform, with comprehensive single-cell DNA analysis to co-detect both SNVs and CNVs. 

  • Detect rare subclones down to 0.1%
  • Resolve clonal architecture
  • Identify mutation co-occurrence
  • “Access to both SNVs and CNVs at the single-cell level, from the same cell, gives us higher resolution to explore tumor evolution and disease progression. We look forward to analyzing these novel data types to help us better resolve the genetic and cellular heterogeneity in cancer.”

    – Samra Turajlic, M.D., Francis Crick Institute, United Kingdom

Why do SNV and CNV analysis?

Cost-efficient sequencing targeting gene-level to chromosome-level CNVs along with SNVs

Quality for your research with best-in-class single-cell DNA accessibility using Tapestri two-step workflow

Flexibility to start Tapestri workflow from cells or nuclei

  • Detect rare subclones down to 0.1%
  • Resolve clonal architecture
  • Identify mutation co-occurrence

The Tapestri Workflow

Sample prep

Simple protocol for cell staining

Library prep

Single workflow combines DNA and protein antibody panels

Sequencing

Single sequencing run for SNVs, CNVs, and proteins

Pipeline

Integrated pipeline for multi-omic analysis

Analysis

Powerful analysis and visualization software

Get SNVs and CNVs from the Tapestri Platform.

Subtitle

Introducing Copy Number Analysis with the Mission Bio TapestriⓇ Platform. The only comprehensive single-cell DNA solution analysis for both SNVs and CNVs simultaneously from the same cell, using a single platform. Hear how to analyze your existing Tapestri Single-Cell DNA sequencing data. Uncover potential CNVs and Loss of Heterozygosity (LOH) from your single-cell datasets and find out if they co-occur with SNVs or indels.

Kelly Kaihara, PHD,
Market Development, Mission Bio
Robert Durruthy-Durruthy, PHD,
Support Team, Mission Bio

  • Detect rare subclones down to 0.1%
  • Resolve clonal architecture
  • Identify mutation co-occurrence